NB 001
CAS No. 686301-48-4
NB 001 ( NB001;NB-001 )
产品货号. M15621 CAS No. 686301-48-4
A potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1798 | 有现货 |
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10MG | ¥2657 | 有现货 |
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25MG | ¥4479 | 有现货 |
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50MG | ¥6391 | 有现货 |
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100MG | ¥8667 | 有现货 |
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500MG | ¥17415 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称NB 001
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述A potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition).
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产品描述A potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition); displays >10-fold selectivity over AC5/6/7/8; shows analgesic effect in animal models of neuropathic pain, without no significant effect on behavioral anxiety.
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同义词NB001;NB-001
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通路Metabolic Enzyme/Protease
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靶点Adenylate Cyclase
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受体Adenylate Cyclase
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研究领域——
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适应症——
化学信息
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CAS Number686301-48-4
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分子量264.33
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分子式C12H20N6O
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纯度>98% (HPLC)
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溶解度——
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SMILESOCCCCCNCCN1C=NC2=C(N)N=CN=C12
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化学全称5-[[2-(6-amino-9H-purin-9-yl)ethyl]amino]-1-pentanol
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Wang H, et al. Sci Transl Med. 2011 Jan 12;3(65):65ra3.
2. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.
3. Zhang MM, et al. Mol Brain. 2014 Jun 16;7:47.
4. Sethna F, et al. Nat Commun. 2017 Feb 20;8:14359.
2. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.
3. Zhang MM, et al. Mol Brain. 2014 Jun 16;7:47.
4. Sethna F, et al. Nat Commun. 2017 Feb 20;8:14359.
产品手册
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