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NB 001

CAS No. 686301-48-4

NB 001 ( NB001;NB-001 )

产品货号. M15621 CAS No. 686301-48-4

A potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1798 有现货
10MG ¥2657 有现货
25MG ¥4479 有现货
50MG ¥6391 有现货
100MG ¥8667 有现货
500MG ¥17415 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    NB 001
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition).
  • 产品描述
    A potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition); displays >10-fold selectivity over AC5/6/7/8; shows analgesic effect in animal models of neuropathic pain, without no significant effect on behavioral anxiety.
  • 同义词
    NB001;NB-001
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    Adenylate Cyclase
  • 受体
    Adenylate Cyclase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    686301-48-4
  • 分子量
    264.33
  • 分子式
    C12H20N6O
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    OCCCCCNCCN1C=NC2=C(N)N=CN=C12
  • 化学全称
    5-[[2-(6-amino-9H-purin-9-yl)ethyl]amino]-1-pentanol

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Wang H, et al. Sci Transl Med. 2011 Jan 12;3(65):65ra3.
2. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.
3. Zhang MM, et al. Mol Brain. 2014 Jun 16;7:47.
4. Sethna F, et al. Nat Commun. 2017 Feb 20;8:14359.
产品手册
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